The Trigatti laboratory is part of the Department of Biochemistry and Biomedical Sciences at McMaster University and the Thrombosis and Atherosclerosis Research Institute of McMaster University and Hamilton Health Sciences in Hamilton, Ontario, Canada.

Our research is focused on the molecular mechanisms involved in the development of atherosclerosis, a chronic inflammatory disease characterized by the development of cholesterol-rich plaques in the arteries. Atherosclerosis is one of the major causes of coronary heart disease and a leading cause of hospitalization and death worldwide. Using mouse molecular genetics, we aim to determine and characterize the contributions of a variety of physiological pathways involved in atherosclerotic development and resulting cardiovascular disease. 

Our Research is Supported by: